"I think it's highly unlikely that he will start," head coach Kyle Shanahan told reporters Friday.

Recently signed kicker Eddy Pineiro made a 35-yard field goal on the final play to give the San Francisco 49ers a 16-15 win over the Arizona Cardinals for their third straight win to open the season.

Though Purdy was a limited participant in practice throughout the week and is progressing more quickly than the 49ers anticipated in his recovery from turf toe as well as an AC joint sprain of his no...

The San Francisco 49ers were without Brock Purdy, their starting quarterback, but it was still a proving ground for these Cardinals. With the game in their hands, the Cardinals squandered the opportunity,

The Cardinals (2-0) are coming off a 27-22 win against the Carolina Panthers in their NFL Week 2 game.

San Francisco has won twice against the spread this year.