Introduction: The sinoatrial node (SAN) is heterogeneous and comprises pacemaker cells (PCs), atrial cardiomyocytes (ACMs), transitional zone (TZ) cells, and stromal cells. Epicardial cells (Epics) ...
Researchers uncovered a key cellular regulator, PP2A-B55alpha, that controls both the cleanup of damaged mitochondria and the creation of new ones. In Parkinson’s disease models, reducing this ...
A key switch for cellular energy balance has been discovered in cells, and it could potentially become the target of new therapies for diseases ranging from Parkinson's to rare disorders caused by ...
Stanford Cardiovascular Institute (S.L., P.H., D.L., W.R.G., D.T.P., F.X.G., N.B., S.M.W.), Stanford University School of Medicine, CA. Department of ...
WASHINGTON, Sept 8 (Reuters) - New research has identified yet another way that spaceflight tampers with the human body. A study involving samples flown on four SpaceX resupply missions to the ...
A first-in-human Phase I study of SHR-4849 (IDE849), a Delta-like ligand 3 (DLL3)-directed antibody-drug conjugate (ADC), demonstrated manageable safety and early signs of anti-tumor activity in ...
Findings reveal space-induced genetic, mitochondrial and inflammatory stress in blood-forming stem cells, offering insight into aging and risk of disease during long-duration space travel. Catriona ...
SAN FRANCISCO--(BUSINESS WIRE)--Tahoe Therapeutics today announced $30 million in new funding to build the definitive foundational dataset for training Virtual Cell Models. With this, the team will ...
Scientists at Johns Hopkins have grown a first-of-its-kind organoid mimicking an entire human brain, complete with rudimentary blood vessels and neural activity. This new "multi-region brain organoid" ...
Faculty of Chemistry, Jagiellonian University in Krakow, Gronostajowa 2, Krakow 30-387, Poland Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University in Krakow, ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pluripotent stem cell (PSC)–derived kidney ...
Reprinted with permission from World at Large. Researchers have discovered that the active compound in psychedelic mushrooms can extend lifespan and reduce cellular aging by 50% in human cells and 30% ...