A team of scientists at the University of Seville has identified an essential process that protects DNA integrity in reproductive cells, providing new clues about how organisms avoid genetic defects ...

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Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chromatin remodellers play a crucial role in ...

The secret to the naked mole-rats' extraordinarily long life may lie in subtle changes to just four amino acids, researchers report. According to a new study, evolutionary mutations in cGAS – an ...

A clump of proteins seems to be in charge of the level of DNA repair that takes place in our bodies, determining how fast mutations accumulate in our cells over a lifetime – and might thus affect our ...

DEAR MISS MANNERS: I have asked my friends to help me swap an engine on my pickup truck, and they have generously agreed. Mechanic etiquette says that if your friends are helping you on a car project, ...

Gene editing has made huge leaps in recent years, such as treating the congenital blood disorders sickle cell anemia and beta thalassemia, which can require lifelong blood transfusions. But scientists ...

Targeted DNA editing by CRISPR technology has great potential for applications in biotechnology and gene therapy. However, precise gene editing remains a challenge largely due to insufficient control ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...