The San Francisco 49ers and Arizona Cardinals will meet on Sunday for an NFC West battle in Week 3. Here's what fans should ...

The San Francisco 49ers returned to the practice field Friday for their final session before hosting the Arizona Cardinals in ...

In a memo sent on Friday, the NFL informed all teams that it is within their "exclusive discretion" to determine whether ...

The San Francisco 49ers have had a tough time with the Arizona Cardinals since head coach Kyle Shanahan took over in the ...

All-white throwback jerseys are to serve as the 49ers' heat shield if Sunday's home opener with Arizona turns into another ...

The San Francisco 49ers haven't ruled out the possibility that quarterback Brock Purdy could return this Sunday against the ...

A judge ruled on Friday that the teenager who allegedly shot 49ers receiver Ricky Pearsall in September 2024 will be tried as ...

San Francisco 49ers defensive coordinator Robert Saleh, offensive coordinator Klay Kubiak, and quarterbacks Brock Purdy and Mac Jones addressed reporters following Thursday's practice as the team ...

Barring a significant last-minute change, the San Francisco 49ers will start Mac Jones at quarterback for a second ...

The Cardinals are set to be thin at cornerback for Sunday's game against the 49ers. Second-round pick Will Johnson is listed ...

Watch Matt Maiocco’s full interview with Kyle Shanahan on “49ers Game Plan,” airing at 9 p.m. PT Friday on NBC Sports ...

Broadcast and streaming information for the San Francisco 49ers Week 3 matchup against the Arizona Cardinals at ...