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Arizona Cardinals vs. San Francisco 49ers live updates

Arizona Cardinals fall to San Francisco 49ers in 1st loss of season

The Arizona Cardinals continue their 2025 NFL regular season schedule with an NFL Week 3 game against the San Francisco 49ers today.

· 16h

49ers vs. Cardinals takeaways: San Francisco edges Arizona on game-winning field goal

· 13h

Arizona Cardinals vs San Francisco 49ers schedule, TV channel for NFL Week 3 game Sunday

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2025 NFL Week 3 schedule: How to watch today's games

The Week 3 NFL lineup for Sunday should have plenty of excitement on the field.

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How to Watch Panthers vs. Falcons: Time, TV Channel and Live Stream – 2025 Week 3

· 17h

Where to watch 49ers vs. Cardinals NFL Week 3 game today on free streams, TV

Cards Wire · 5h

Cardinals-49ers final score: San Fran gets 16-15 win on last-second field goal

Both teams are 2-0 and, with the loss by the Los Angeles Rams, the winner of this game will have sole possession of first place in the NFC West, three games into the season.

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Arizona Cardinals vs. San Francisco 49ers NFL game: How to watch, kickoff time, TV channel and more

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Cardinals vs. 49ers: How to watch, TV schedule, radio broadcast, live stream and more

Arizona Cardinals RB carted off field in Week 3

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Cards Wire · 13h

James Conner injury: Arizona Cardinals RB carted off field in Week 3

Running back James Conner suffered a gruesome ankle injury in the second half of their game against the San Francisco 49ers.

· 12h

Arizona Cardinals get bad news on running back James Conner's injury

· 2h · on MSN

With Cardinals RB James Conner out, Trey Benson, backups step up

· 13h

Arizona Cardinals running back James Conner exits with apparent serious leg injury

Running back James Conner was carted off the field with an ankle injury early in the third quarter of their Week 3 game against the San Francisco 49ers.

· 10h

James Conner injury update: Cardinals RB out long-term after suffering severe ankle injury vs. 49ers

· 14h

James Conner injury: Cardinals RB suffers ankle injury in Week 3

16h

San Francisco 49ers inactives: QB Brock Purdy, WR Jauan Jennings out vs. Cardinals

The San Francisco 49ers entered Week 3 against the Arizona Cardinals without several important offensive players. Quarterback Brock Purdy and receiver Jauan Jennings were initially questionable to play on the final injury report of the week, but they were both downgraded Sunday morning.

Arizona Cardinals at San Francisco 49ers: Predictions, picks and odds for NFL Week 3 game

USA Today's NFL experts make their picks for a Week 3 showdown between the San Francisco 49ers and Arizona Cardinals