Elevated WNT signalling triggers a wound-like response in RAS cancer cells, activating TLRs-dependent canonical NF-κB ...
Parabilis Medicines, a clinical-stage biopharmaceutical company committed to creating extraordinary medicines for people living with cancer, today announced preliminary clinical and preclinical ...
Parabilis Medicines, a clinical-stage biopharmaceutical company committed to creating extraordinary medicines for people ...
First orphan designation ever granted to a condensate-modulating therapeuticBuilds on recent IND opening for DPTX3186, a ...
Oral therapy showed dose-dependent increases in progranulin protein levels in both plasma and cerebrospinal fluid; >95% mean increase in progranulin levels in CSF, compared to baseline; favorable ...
The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to DPTX3186, an investigational therapy being ...
First orphan designation ever granted to a condensate-modulating tBuilds on recent IND opening for DPTX3186, a first-in-class oral condensate modulator targeting the Wnt/β-catenin pathwayProvides key ...
US biotech Dewpoint Therapeutics has announced that the US Food and Drug Administration (FDA) has granted Orphan Drug ...
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