Deoxyhypusine synthase (DHPS), which activates the eukaryotic translation initiation factor 5A, shows potential as a therapeutic target against melanoma, which is quite aggressive and prone to ...

Could yeast and humans be any more different? Going by looks alone, probably not. But peering into our genomes reveals ...

Most current approaches rely on adding nuclear localization signal (NLS) motifs to the ends of Cas9 to facilitate nuclear entry. However, this method is inefficient, and much of the Cas9 that is ...

An RNAi based genetic screen and subsequent analyses reveal how dyneins and small GTPases coordinate autophagosome positioning at the ncMTOC in fat cells, advancing understanding of autophagic vesicle ...

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Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...