Chaperone-mediated autophagy prevents loss of brown adipose tissue activity during aging

As the body ages, brown adipose tissue activity decreases, fewer calories are burned, and this can contribute to obesity and ...

Arvinas to Present Preclinical Data for ARV-393 at the 2025 American Society of Hematology (ASH) Annual Meeting

Arvinas, Inc. (Nasdaq: ARVN), a clinical-stage biotechnology company creating a new class of drugs based on targeted protein ...

Beam Therapeutics to Present Updated Data from BEACON Phase 1/2 Trial of BEAM-101 in Sickle Cell Disease at American Society of Hematology (ASH) Annual Meeting

Inc. (Nasdaq: BEAM), a biotechnology company developing precision genetic medicines through base editing, today announced that the company will present updated safety and efficacy data from the BEACON ...
eLife

Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

This important study examines the potential role of ARHGAP36 transcriptional regulation by FOXC1 in controlling sonic hedgehog signaling in human neuroblastoma. While there are many solid findings ...
PNAS

Structural insights into proteolysis-dependent and -independent suppression of the master regulator DELLA by the gibberellin receptor

Contributed by Tai-ping Sun; received May 6, 2025; accepted July 7, 2025; reviewed by Huilin Li, Makoto Matsuoka, and Claus Schwechheimer ...