Insights from worms could help scientists harness the power of dietary restriction for longevity

The pursuit of a longer life may currently be trending for tech bros, but the notion of a fountain of youth, or even ...

Enzyme motif reveals how plastic-munching bacteria are evolving across the seven seas

Deep within the world's oceans lurk marine bacteria armed with plastic-munching enzymes, their evolution seemingly sculpted ...

Scientists uncover key mechanisms that drive an enzyme linked to aging and cancer

Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the ...
Johns Hopkins Medicine

Protein Plays Unexpected Dual Role in Protecting Brain from Oxidative Stress Damage

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the ...
eLife

Herbivorous insects independently evolved salivary effectors to regulate plant immunity by destabilizing the malectin-LRR RLP NtRLP4

State Key Laboratory for Quality and Safety of Agro-Products, Key Laboratory of Biotechnology in Plant Protection of MARA, Zhejiang Key Laboratory of Green Plant Protection, Institute of Plant ...
C&EN

Nanoscale Temperature Increases Are Not Required for Molecular Stimulation Using Nanoparticles under Radiofrequency Magnetic Fields: A Thermal Energy Flux Mechanism of Remote ...

Radiofrequency heating of enzymes promises to be a remote method to selectively stimulate molecular activity near the surface of heated particles while leaving the background temperature and ...
FierceBiotech

Denali's Hunter syndrome drug latest to be hit by FDA decision delay

Denali Therapeutics has become the latest on a growing list of biotechs to experience an FDA review delay in recent months. The agency in July accepted an application for Denali's enzyme replacement ...
Medical Xpress

Targeting enzymes to weaken cancer cells could supercharge prostate cancer treatment

An international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment for one of the most common cancers affecting men. The research, published in the ...
Business Wire

Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB)

SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Spruce Biosciences, Inc. (Nasdaq: SPRB), a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for neurological ...
C&EN

Fabrication of Hierarchically Mesoporous Multishelled Metal–Organic Frameworks via Template-Induced Assembly/Grinding Strategy for Immobilization of Enzyme and Enhancing ...

Beijing National Laboratory for Molecular Sciences; Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China ...