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New in vitro results show Telomir-1 adds KDM5 family inhibition to its previously reported KDM2/KDM6 and DNA methylation ...
Ubiquitin controls the lifespan and distribution of proteins in the cell, but it can also determine their shape, function, or ...
18hon MSN
Reprogramming the epigenetic code affects growth and survival of tumor cells in multiple myeloma
In the cancer type multiple myeloma, the malignant cells differ significantly from normal cells regarding the layer of ...
Sacubitril/valsartan shows evidence of benefit in the first randomized trial evaluating a drug treatment for patients with ...
The stock-trading website Raging Bull just gave Cocrystal Pharma, a clinical-stage biotech, a big thumbs up for its ...
The outlook for the KAT6 inhibitors market is strengthening as interest in epigenetic targets grows and KAT6A/B gain ...
As the prevalence of both chronic kidney disease (CKD) and heart failure (HF) increases, therapies targeting shared pathways ...
In preclinical models, rat insulinoma‑derived beta‑cell line INS‑1 (INS‑1) cells and mouse islets showed rapid, robust ...
Brabant Development Agency (BOM) and angel investor join lead investor Libertatis Ergo Holding (LEH) in providing funding, with additional ...
9don MSN
Proof-of-concept innate immune checkpoint inhibitor shows promise against solid tumors in rodents
Cancer immunotherapy, which primes the body's immune system to fight off tumors, has historically focused on harnessing T ...
Aldosterone increases blood pressure and contributes to chronic kidney disease (CKD) progression. Trial findings suggest baxdrostat may be an effective treatment.
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