Most leaders manage time. The best ones manage rhythm and align their team’s energy, capacity, and timing to turn effort into ...

This paper describes Unbend - a new method for measuring and correcting motions in cryo-EM images, with a particular emphasis on more challenging in situ samples such as lamella and whole cells. The ...

Diabetes is a chronic condition characterized by elevated blood glucose levels, stemming from the body's inability to produce enough insulin ...

The hidden Markov model (HMM), a statistical model widely applied in machine learning, has proven effective in addressing various problems in ...

Abstract: Sequence alignment is a fundamental step in genomic data analysis. Third-generation sequencing technology facilitates the acquisition of high-quality genomic data but the explosive growth of ...

Abstract: Sequence-to-graph alignment is a critical component of pan-genome-based read alignment and represents the most computationally intensive step in this process. To address this challenge, we ...

For PCR screening of the astA gene, 2,726 E. coli strains isolated from stool specimens of diarrheal children who visited clinics in Kagoshima, Japan, from 2013 to 2020 (referred to as Kagoshima ...

Background: The Immunoglobulin Kappa Constant (IGKC) gene encodes the constant region of the immunoglobulin kappa light chain, a crucial component of antibodies. Despite its important biological role, ...

Bruton’s Tyrosine Kinase (BTK) is an important target in cancer treatment, motivating studies into its mechanism. Like many other tyrosine kinases, BTK contains an SH2 domain that binds to ...