San Francisco 49ers kicker Eddy Piñeiro, center, celebrates his game-winning field goal after an NFL football game against the Arizona Cardinals, Sunday, Sept. 21, 2025, in Santa Clara, Calif.

The San Francisco 49ers are unbeaten and alone in first place, but a pall hangs over the team after Nick Bosa became their latest star to be forced off the field by an injury.

The 49ers (3-0) won their home opener 16-15 on Eddy Pineiro’s walk-off field goal against the Arizona Cardinals.

The San Francisco 49ers had to finish the end of their contest against the Arizona Cardinals without a key piece of the defense.

Ricky Pearsall is undisputedly the San Francisco 49ers' best offensive weapon this season. We're three weeks into the 2025 season, and his performance against t

The San Francisco 49ers have dealt with plenty of offensive injuries this year, but the defense is taking several hits in Week 3.

Purdy was initially feared to be out for as long as five weeks, but he's reportedly been making steady progress. Rapoport's post said Purdy's return "is coming," and the show's graphic said Purdy is "likely to return" by Week 4 against the Jaguars.

Quarterback Mac Jones, already serving in relief duty for the injured Brock Purdy, told reporters after Sunday's 16-15 win over the Arizona Cardinals that he reaggravated the same PCL sprain that hampered him during training camp.

The San Francisco 49ers continue to get hit by the injury bug, as the team has revealed the status for both quarterback Brock Purdy and wide receiver Jauan Jennings.