How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

When Daniel Fischer cofounded Tevard Biosciences in 2017, he wasn’t trying to bet on the next hot RNA technology. His interest was more personal. His daughter Natasha has Dravet syndrome, a rare form ...

For disorders driven by a known genetic component, research understandably focuses on developing a drug targeting that genetic signature. When that works, the outcome benefits patients but the end ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Daniel E. Eyler, Monika K. Franco, Zahra Batool, Monica Z. Wu, Michelle L. Dubuke, Malgorzata Dobosz-Bartoszek, Joshua D. Jones, Yury S. Polikanov, Bijoyita Roy, Kristin S. Koutmo Proceedings of the ...

During a call with Alltrna co-founder and CIO Theonie Anastassiadis and CEO Michelle C. Werner, I’m immediately called upon to dust off my Biology 101 notes to grasp the significance and scope of ...

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...

In a recent study published in the journal Nature, researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria. Protein synthesis by ribosomes ...

Scientists at St. Jude Children’s Research Hospital report that human ribosomes decode messenger RNA (mRNA) 10 times slower than bacterial ribosomes, but do so more accurately. The study “mRNA ...

The researchers found that mRNA-based COVID-19 vaccines could potentially help patients whose tumors don’t respond well to ...