Local anesthetics have transformed clinical practice by enabling a broad range of minor and major procedures with minimal discomfort. Although adverse reactions are frequently reported, genuine ...

All current local anesthetics block sensory signals — pain — but they also interrupt motor signals, which can be problematic. For example, too much epidural anesthesia can prevent mothers in labor ...

A higher intensity of pain during infiltration of local anesthesia during cesarean delivery was associated with increased pain at 24 hours postpartum and lower global health ratings, although the ...

Over the last decade, poisonings and deaths linked to the use of local anesthetics have decreased. Even so, poisonings from one commonly used anesthetic, lidocaine, have increased in the United States ...

Reports of lidocaine poisoning increased but reports of local anesthetic poisonings decreased following the 2010 advisories.