Arginase deficiency is a rare autosomal recessive metabolic disorder that disrupts the final step of the urea cycle, impairing the conversion of arginine into urea and ornithine. In affected ...

A 25-year study at 118 U.S. hospitals has demonstrated the effectiveness of a simple treatment for a mind-destroying, frequently lethal family of genetic diseases called urea cycle disorders. The ...

A physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States. An Indiana University School of Medicine ...