Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts. RNA splicing is a cellular process ...
Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message ...
After a gene is transcribed into RNA, modifications can occur to the subunits or "bases" that make up the RNA molecule, which can affect its structure and function. The study of these changes is known ...
While targeted protein and RNA degradation are hot areas for R&D, the drugs developed so far come with limitations. Now, a new class with broader applications may not be far off. In a study published ...
CRISPR powers everything from gene editing to rapid diagnostics, but how did one of its most versatile branches arise? A new Cell study, “Functional RNA splitting drove the evolutionary emergence of ...
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Single-cell RNA sequencing of bone metastases from multiple cancer types reveals three distinct immune archetypes
Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...
Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early-onset form of diabetes. Smaller-scale mutations in the very same gene are also common and quietly nudge millions of people ...
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