Scientists first observed the biological phenomenon of restriction and modification in the 1950s, but they did not identify and isolate restriction enzymes until the late 1960s. 3 In 1970, Hamilton ...

DNA restriction-modification enzymes are enzymes involved in DNA restriction modification. They include DNA restriction endonucleases (restriction enzymes) and their companion modification methylase ...

The restriction endonuclease map of the 25 S and 18 S ribosomal RNA genes of a higher plant is presented. Soybean (Glycine max) rDNA was enriched by preparative buoyant density centrifugation in ...

We describe the molecular cloning of the gal operon of Salmonella typhimurium LT2 and the localization of the gal promoter and the genes galE, galT, and galK. The order of the genes and the direction ...

In many organisms the primary DNA structure is covalently modified to regulate, for example, gene expression and genome structure. In eukaryotes, the dominant modification is methylcytosine, although ...