Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling ...

Tokyo, Japan – Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a ...

A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...

Two competing models exist for homologous recombination. The results of this study support a model where the double-stranded DNA is not unwound during the homology search. (Shibata et al. Nucleic ...

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...

CN signatures were prevalent across cancer types and associated with diverse processes including focal tandem duplications, seismic amplifications, genome-wide loss of heterozygosity (gLOH), and HRD.

Using optical tweezers, researchers at National Taiwan University have observed individual binding events in real time, ...

The chloroplast and mitochondrial genomes are essential for photosynthesis and respiration, respectively. RECA and RECG, which are plant-specific homologs of the bacterial homologous recombination ...

The Association for Molecular Pathology announced the publication of best practice recommendations for clinical laboratories developing and performing homologous recombination deficiency (HRD) testing ...

Wei-Hsuan Lan, Sheng-Yao Lin, Chih-Yuan Kao, Wen-Hsuan Chang, Hsin-Yi Yeh, Hao-Yen Chang, Peter Chi, Hung-Wen Li Proceedings of the National Academy of Sciences of the United States of America, Vol.