Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Our understanding of the complex regulation of protein synthesis and its integration with other steps of gene expression such as mRNA decay has dramatically increased. Furthermore, we are gaining ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival. Bacteria are no exception, with molecular machines involved in ...

Proteins sourced from microorganisms are attracting attention for their potential in biomanufacturing a variety of products, ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 27 (July 5, 2016), pp. 7545-7550 (6 pages) Regulation of protein synthesis plays a vital role in ...

HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...

To better understand how RNA in bacteria gives rise to protein -- and potentially target these processes in the design of new antibiotics -- researchers are turning their attention to the unique way ...