Nature

Genetic Polymorphisms and Treatment Outcomes in Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer (NSCLC) remains one of the leading causes of cancer-related mortality worldwide. Genetic polymorphisms—particularly single nucleotide polymorphisms (SNPs)—in genes that ...
ascopubs.org

Association between glutathione s-transferase P1 polymorphisms and time to tumor progression in small cell lung cancer patients.

Breast cancer in the Kingdom of Saudi Arabia: A review of all female breast cancer cases from the Saudi Cancer Registry (SCR) from 1994-2004. Background: Many of commonly used chemotherapeutics in ...
ascopubs.org

Single nucleotide polymorphisms (SNPs) of hypoxia-related and DNA repair genes associated with toxicity and clinical outcome in head and neck squamous cell carcinoma patients ...

Evaluating the cost-effectiveness of low-level laser therapy (LLLT) in head and neck cancer patients submitted to concurrent chemoradiation. This is an ASCO Meeting Abstract from the 2013 ASCO Annual ...

Structural variants reshape the yeast genotype–phenotype map

Université de Strasbourg and partners report that adding structural variants and small insertion–deletion mutations to single ...
Labroots

Enhancer-Promoter Interactome Drives Neuronal Cell Differentiation and Contextualizes Alzheimer's Associated Polymorphisms

Chromatin Immunoprecipitation, coupled with sequencing, has shaped our understanding of how transcriptional machinery interacts with genomes to facilitate gene regulation. These protein-DNA ...
EurekAlert!

TOAnnoPriDB: an integrative database for trans-omic annotation and prioritization of non-coding variants across human genome

In recent years, the development of large-scale sequencing projects has identified numerous genomic variants in the human genome. For instance, the NyuWa genome resource (Cell Reports, 2021), led by ...