We had four matchups of former No. 1 overall picks take place on Sunday, with Matthew Stafford facing off against Cam Ward, Joe Burrow going up against Trevor Lawrence, Jared Goff doing battle with Caleb Williams and Kyler Murray clashing with Bryce Young .

Seattle is 0-1 on the year and Pittsburgh is 1-0. The Seahawks are without Devon Witherspoon and Nick Emmanwori, making their hopes of an upset win even more challenging. However, this is the NFL, and it's an "any given Sunday" kind of league. Follow along with our live updates! Final. Seattle has their first win in 2025.

Las Vegas Raiders vs Los Angeles Chargers picks, predictions, win probabilities for NFL Week 2 Monday Night Football game on Sept. 15. Who will win?

A set of exact Week 3 NFL score predictions can give you the tools needed to make a variety of picks for every game, as well as a guide for some NFL props you could target as well. Hitting on an exact NFL score prediction could also result in a huge payday.

James Cook had a huge day for the Buffalo Bills and has been named one of the top winners in the NFL from Week 2.

Cam Ward is set to play his first NFL regular-season game Sunday in the Tennessee Titans' home opener against the Los Angeles Rams.

The Chicago Bears had a crushing loss. While Vikings quarterback J.J. McCarthy survived a slow start to later take over the game.