Researchers have changed the way to look at DNA. They show that DNA is much more than a linear sequence of building blocks; it has a 3D structure that influences the variation of human genome-wide ...

Proteins are like Spider-Man in the multiverse. The underlying story is the same: each building block of a protein is based on a three-letter DNA code. However, change one letter, and the same protein ...

The topographical features of DNA in the body may dictate where and when cancer-causing mutations appear in its code. When you purchase through links on our site, we may earn an affiliate commission.

Scientists in the U.S. have described how the DNA double helix contains an intrinsic timer that determines how often mutations might occur spontaneously. The team led by Ohio State University’s Zucai ...

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601 Sequencing data from 56,965 ...

Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of ...

New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining ...

DURHAM, N.C. -- Biochemists have pinpointed how a flaw in DNA that is central to mutations in cancer and aging fools the cellular enzyme that copies DNA. Their finding explains how oxidative DNA ...

Targeting ERBB2 (HER2) Amplification Identified by Next-Generation Sequencing in Patients With Advanced or Metastatic Solid Tumors Beyond Conventional Indications Patients with advanced HR-DDR mut ...

Together with other versions of CRISPR/Cas9, the new editors offer scientists an expanded set of precision tools for correcting diseases. CRISPR/Cas9 is a molecular scissors that snips DNA. Scientists ...