Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

Effective protein characterization depends on the precise isolation and fragmentation of peptide ions within the mass spectrometer, typically coupled with liquid chromatography (LC-MS/MS). In a ...

MALDI remains a powerful tool for analyzing large biomolecules with minimal fragmentation. In this process, peptides or proteins are co-crystallized with a matrix on a metal plate. A laser pulse ...

Automatic acquisition and processing of mass-spectral data / R. Venkataraghavan -- Photographic techniques in organic high-resolution mass spectrometry / Dominic M. Desiderio, Jr. -- The electrical ...

The world's most widely used and trusted resource for identifying mass spectra, the "fingerprints" of molecules, has undergone a major expansion, according to its managers at the National Institute of ...

In a recent review article published in the journal Annual Review of Analytical Chemistry, researchers highlighted the transformative role of machine learning (ML) in advancing mass spectrometry (MS) ...

A disassembled charge-detection mass spectrometry ion trap. A disassembled charge detection mass spectrometry ion trap Credit: Gwendolyn Jarrold At the University of Oxford, Justin Benesch studies ...

“Better, faster, stronger” is the mantra that has defined the last 15 years of the omics era. The rise of next-generation sequencing in microbial genomics is a perfect example. Progressive gains in ...

A new software improves data-independent acquisition proteomics by providing a computational workflow that permits highly sensitive and accurate data analysis. Proteomics produces enormous amounts of ...

While many people often use spectroscopy and spectrometry interchangeably, there are some subtle differences in their exact meanings and the associated experimental techniques they are used to ...