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Restriction Fragment Length Polymorphism (RFLP) Technique

Restriction fragment length polymorphism (RFLP) is a technique invented in 1984 by the English scientist Alec Jeffreys during research into hereditary diseases. It is used for the analysis of unique ...
Nature

General Cystic Fibrosis Mutations Are Usually Missense Mutations Affecting Two Specific Protein Domains and Associated with a Specific RFLP Marker Haplotype

Cystic fibrosis (CF) is an autosomal recessive disease due to a deleterious mutation in a chloride channel gene (CFTR = CF transmembrane conductance regulator), located on chromosome 7. From a ...
JSTOR Daily

PCR-RFLP Typing of UreC from Helicobacter pylori Isolated in Argentina from Gastric Biopsies before and after Treatment with Clarithromycin

This is a preview. Log in through your library . Abstract A clinical trial was conducted in Argentina to determine the efficacy of clarithromycin plus lansoprazole for the treatment of Helicobacter ...
Nature

Isolation of 2 novel RFLP markers and their localization at 2q35 by microdissection and subsequent enzymatic amplification

We previously constructed a chromosome 2q-specific genomic libary and isolated a number of microclones. In the present study, we first analyzed with Southern hybridization whether any of the ...