Pressure from surrounding tissues activates invasive programs in cancer cells. This mechanical stress rewires epigenetic regulation. Cancer cells are notoriously adaptable, capable of shifting their ...

Tracking how cancer cells develop in real time How these differences in the genome and in epigenetic control arise in cells, and how they are passed on to their daughter and granddaughter cells, has ...

As blood cancers are constantly evolving and developing mutations that grow resistance to current treatments, researchers in ...

The immune system is comprised of two separate active arms of immunity to provide robust protection against disease. The two separate systems of immunity include the innate and adaptive immune ...

Telomere damage drives T cell exhaustion. Antioxidants restored their cancer-fighting strength in mice. Tumor environments place heavy stress on immune cells that fight cancer. Limited oxygen, ...

Cancer cells respond to stress with greater diversity. Drugs that affect DNA replication, or radiation that causes direct DNA damage, lead to increasingly diverse offspring over multiple cell ...

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired ...

An international team of scientists led by researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College ...

Dormant cancer cells pose a unique challenge to doctors because they can remain invisible in tissues for decades. According ...

The American Cancer Society awarded 14 new Discovery Boost grants and 4 new Mission Boost grants across 17 institutions this ...

Scientists have developed a tool that can predict how bowel cancer adapts to treatment – helping researchers to design new personalized drugs that will keep patients living well for longer. A team ...