Replication-dependent histone mRNAs, which encode the most abundant histone proteins, are the only known cellular mRNAs that are not polyadenylated. Instead they end in a conserved stem–loop that ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 31 (Aug. 3, 2004), pp. 11380-11385 (6 pages) An E2 ubiquitin-conjugating enzyme, Rad6, working with an E3 ...
LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene sequences. While each cell contains the complete genetic blueprint of an organism, chemical marks ...
Phase II, Randomized, Controlled, Double-Blinded Trial of Weekly Elesclomol Plus Paclitaxel Versus Paclitaxel Alone for Stage IV Metastatic Melanoma Epigenetic processes are implicated in cancer ...
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