A new research perspective was published in Oncotarget's Volume 15 on January 24, 2024, entitled, "Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic ...

Individuals with a genetic profile that puts them at risk of obesity may not necessarily be at risk of having high ...

Although a large majority of head and neck cancers (HNC) have a deregulation of the PI3K/AKT/mTOR pathway, deregulation of this pathway does not necessarily signify that the tumor is dependent on it ...

Effect of AXL on cholangiocarcinoma survival and sensitivity to cytotoxic chemotherapy. Significance of alterations in DNA damage repair (DDR) genes in advanced biliary cancers (ABCs) treated with ...

Researchers from the University of Southern Denmark and Odense University Hospital have studied tissue from patients with atherosclerosis. They found that many of the cells in the diseased tissue ...

Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence ...

Researchers discovered a genetic mutation that could explain why some individuals thrive on as little as three hours of sleep per night. The study, published on May 5 in the journal Proceedings of the ...

These unintended interactions can lead to harmful alterations in essential genes, disrupting cellular processes and impairing the immune response. A significant cause of these off-target effects is a ...