Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human ...

An international team, including researchers from HSE University, has created the first comprehensive map of ...

Switches' in our DNA that affect gene activity in cells could be crucial to understanding and possibly treating Alzheimer's ...

Organisms are made up of cells, and in each of those cells, a genome encodes the instructions for that organism to grow and survive. The human genome has at least 20,000 genes, and the expression of ...

Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells. What determines these differences? It all comes down to gene ...

Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer ...

Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer modeling, ...

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...