New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, ...

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse ...

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse ...

The β 2-adrenergic receptor (β 2-AR) is a typical G-proteincoupled receptor (GPCR) with rich pharmacology and has been targeted for treating various diseases such as asthma, chronic obstructive ...

Receptors on cell surfaces translate an outer signal into a response inside the cell. By this, they are responsible for a plethora of essential processes in living organisms. But what if we could ...

Altering the chemical properties of an anti-nausea drug enables it to enter the endosomal compartments inside the cell and provide long-lasting pain relief, according to a new study led by researchers ...

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse ...