Overview of peripheral and central insulin actions (black arrows). The vast majority of insulin hormones are synthesized by the pancreas. Insulin crosses the blood‒brain barrier (BBB) to act within ...

Researchers provide a comprehensive overview of the blood-brain barrier (BBB), detailing its cellular architecture, transport ...

Insulin is a glucose-lowering hormone that targets the peripheral tissues, especially the skeletal muscle and fatty tissues. Insulin also circulates throughout the brain, wherein it can impact the ...

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer’s disease and ...

A 5-day high-caloric diet triggered liver fat accumulation and disrupted brain insulin action in men with a healthy body weight, with effects persisting even after resuming a normal diet. Researchers ...

A recent study suggests that two existing drugs, empagliflozin and an experimental insulin nasal spray, may help enhance ...

"For the first time, we found that empagliflozin, an established diabetes and heart medication, reduced markers of brain ...

More than a decade ago, researchers found that an acute complication of type 1 diabetes, diabetic ketoacidosis (DKA), can be resolved with the hormone leptin, even in the absence of insulin. DKA ...

When six infants around the world were diagnosed with an odd trio of symptoms (diabetes, epilepsy, and abnormally small heads ...