Cells send signals through enzyme cascades, where one enzyme passes the signal to the next. In such cascades, it is crucial that the enzyme recognizes the right substrates to ensure that, for example, ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Enzymes are biological catalysts that facilitate biochemical transformations. An international team of bioinformatics researchers has developed a new process for predicting Michaelis constants, which ...