DNA, often called the blueprint of life, is built from four chemical building blocks known as deoxy-nucleoside triphosphates ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

They observe how the mobile DNA LINE-1 copies its sequence in human cells, revealing the precise mechanism of the ORF2p gene.

A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines. DNA ...

A new study from Karolinska Institutet, published in Nature Communications, reveals that cyclin-dependent kinases (CDK) promote DNA replication licensing in human cells by relieving inhibitory signals ...