In such cases, DNA repair pathways - such a vital physiological process in normal life - can be hijacked by cancer cells who use them to resist the effects of chemotherapy drugs.

An aging expert thinks humans can live for 20,000 years—and he might not be crazy. There's one major key to unlocking extreme ...

Their work on Frontier will involve examining transcription-coupled NER, which is a DNA repair process that fixes damage in actively transcribed genes to ensure that essential proteins can ...

DNA damage has been associated with aging and disease. Double-strand breaks are one of the worst forms of damage. New research shines a light on the repair process.

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or stop disease progression.

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

Scientists have developed a new more precise gene editing technique that uses AI to predict how cells repair their DNA.

Each cell in our body experiences up to tens of thousands of DNA-damaging events per day, primarily from routine cellular maintenance or exposure to toxins in our environment. Despite the high ...

DNA lesions are repaired by a cut-and-remove process called nucleotide excision repair. An in vitro biochemically defined system has been developed in which six repair factors are sufficient to excise ...

Zooming in on individual cells The body has various mechanisms to repair DNA, but the process can differ from cell to cell. This makes it important to study DNA repair in individual cells.

Could DNA be glycosylated? A new study published in Engineering explores this intriguing question, suggesting that DNA might undergo glycosylation, a process that could revolutionize our understanding ...