Purpose: To evaluate the sensitivity, specificity, advantages, and limitations of multiplex ligation-dependent probe amplification compared with conventional karyotype analysis in the investigation of ...

Cytogenetics is the study of chromosomes, a vital tool to understanding how genetics play a role in the development and progression of certain diseases, as well as to predicting how a person will ...

Multiple myeloma (MM) treatment has changed tremendously, with significant improvement in patient out-comes. One group with a suboptimal benefit is patients with high-risk cytogenetics, as tested by ...

Flow cytometry can be used to measure a number of characteristics of a population of cells and refers to the process of passing cells individually through a single or series of laser beams adjacent to ...

The sophisticated 'cytogenetic facility' to diagnose various types of blood cancer was added to the list of equipments at Indo American Cancer Institute & Research Centre on Saturday. HYDERABAD: The ...

Recent published studies have demonstrated the incremental value of the use of cell-free DNA for noninvasive prenatal testing with 100% sensitivity for trisomies 21 and 18 and a specificity of ≥99.7% ...

EuroGentest has announced a series of initiatives following the European Society of Human Genetics in Amsterdam designed to enhance and harmonise genetic testing across the EU. These include piloting ...

Gemtuzumab ozogamicin, with daunorubicin and cytarabine, is recommended as an option for untreated de novo CD33-positive acute myeloid leukaemia (AML), except acute promyelocytic leukaemia, in people ...

Detection of Chromosome Abnormalities Pre–High-Dose Treatment in Patients Developing Therapy-Related Myelodysplasia and Secondary Acute Myelogenous Leukemia After Treatment for Non-Hodgkin’s Lymphoma ...