A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — plays a vital, overlooked role in the first steps of life. Each of us starts ...
Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer. By blocking a protein called Ant2, they were able to reprogram how these cells ...
A new study has identified taurine, which is made naturally in the body and consumed through some foods, as a key regulator of myeloid cancers such as leukemia. The paper is published in Nature. The ...
A recent Science study explored how intranuclear metabolic enzymes establish the link between locus-specific epigenetic reprogramming of T cells and nutrient availability. Persistent antigen ...
A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...
In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic "map" of how cells orchestrate glucose processing, ...
Researchers find high-fat diets set off metabolic dysfunction in cells, leading to weight gain, but these effects can be reversed by treatment with an antioxidant. Consuming a high-fat diet can lead ...
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Mitochondria and Lysosomes Orchestrate Metabolic States of Regulatory T Cells
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the ...
Scientists have uncovered a hidden weakness in one of the deadliest childhood cancers. The tumors, which spread quickly and are notoriously hard to treat, rely on a sugar-processing pathway to survive ...
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