Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 23 (June 5, 2018), pp. E5307-E5316 (10 pages) The CRISPR-Cas systems of bacterial and archaeal adaptive ...
Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...
The codebreaking works like this. The GenomePAM method maps CRISPR's passwords directly in human cells. Instead of relying on artificial systems that are often limited (e.g., testing 1 to 3 sequences ...
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