Here are five predictions for Sunday’s pivotal game at SoFi Stadium: The Chargers’ rookie out of North Carolina is a powerful and fast player who could not get untracked last week against the Raiders. Najee Harris didn’t fare much better as Justin Herbert led the Chargers in rushing.

View news about the Denver Broncos vs. Los Angeles Chargers game played on September 21, 2025 including player news, injury news, predictions, analysis and more.

Preview the Denver Broncos' NFL Week 3 matchup with the Chargers, including live stream, TV channel, odds, and game information.

The Denver Broncos and Los Angeles Chargers will face off in an AFC West matchup in Week 3. The Chargers have already beaten two division rivals in the Kansas City Chiefs and Las Vegas Raiders.

It's Broncos week! The Los Angeles Chargers will play in front of their home fans for the first time this season as they host their division rival on Sunday. This is technically the Bolts' second home game, as they were deemed such in their Week 1 Brazil win against the Chiefs.

Preview the Los Angeles Chargers' NFL Week 3 matchup with the Broncos, including live stream, TV channel, odds, and game information.

Broncos-Chargers series: Denver’s up 72-57-1 all-time on their AFC West rivals in the regular season. The Broncos, though, are coming off two 2024 losses to the Bolts, as quarterback Justin Herbert and coach Jim Harbaugh’s run game downed Denver in both divisional matchups.

The Denver Broncos will be at a loss when they take on the Los Angeles Chargers, as the team has ruled out two starters ahead of the showdown.