49ers host Matthew Stafford and the Rams

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Five 49ers you should watch in key NFC West showdown vs. Rams in Week 10
Matt Maiocco lists the five 49ers players who must step up in San Francisco's pivotal divisional matchup with the Los Angeles Rams on Sunday.

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Rams Wire on MSN · 4h
Rams-49ers: Expert picks for Week 10
49ers host Matthew Stafford and the Rams in a key NFC West clash

Player the 49ers should have gotten at the trade deadline

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John Lynch explains the 49ers' inactivity at the trade deadline
John Lynch to @knbr on 49ers & trade deadline: "We’re top-4 in the league in trades made this year. We did a lot to improve our team and did to the end. … We weren’t going to make an overpayment.

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John Lynch breaks silence on 49ers’ inactivity at NFL trade deadline
49ers G.M. John Lynch: We weren't going to get fleeced at trade deadline

San Francisco 49ers, Purdy and Brock

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It's time for 49ers QB Brock Purdy to suck it up and play
Sunday, in the media room at MetLife Stadium, where the New York Jets, the New York Giants and NFL players’ ACLs go to die each week, San Francisco 49ers head coach Kyle Shanahan subtly gave the most revealing update on quarterback Brock Purdy’s lingering toe injury.

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49ers' Brock Purdy: Stays limited Thursday
49ers hope to push Brock Purdy's workload this week

Expert says the 49ers are facing a legitimate quarterback controversy

Purdy already has led the 49ers to the NFC Championship Game, and he made a Super Bowl appearance in his first full season as ...

Rams HC Confirms 'The Thiccer Kicker' Harrison Mevis Will Start over Karty vs. 49ers

Los Angeles Rams kicker Harrison Mevis is set to make his NFL debut during Sunday's Week 10 matchup at the San Francisco ...
Rams Wire on MSN

Jared Verse admits Rams-49ers rivalry 'means a little bit more'

Jared Verse says this week's game against the 49ers "means a little bit more," especially after the Rams lost to San ...

Week 10 NFL odds, lines, best bets, predictions: Computer model likes Buccaneers and 49ers

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since ...

Rams vs. 49ers Best Bets, NFL Week 10 Picks Against The Spread, Hot Take 📩

The latest edition of Newsweek Sports Betting 📩 includes Rams vs. 49ers best bets and NFL Week 10 picks against the spread.

How the 49ers’ battered defensive line is fighting through a season from hell

With Nick Bosa and Mykel Williams done for the season and other D-linemen banged-up, DL coach Kris Kocurek has had his job ...

Week 10 NFL odds, picks, predictions: Our 10 NFL best bets, including a play in Rams-49ers

Then there’s this noteworthy trend: While the over has hit in each of the last four Bills-Dolphins meetings in Buffalo and 10 ...

Rams at 49ers prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

Despite a wave of injuries to key position groups, San Francisco has persevered and is right in the thick of an ...

The harsh reality that 49ers fans must accept about Brandon Aiyuk

The 49ers have yet to open the practice window for Brandon Aiyuk to return, which should start to set in a harsh reality.